Targeting the mucus matrix to prevent peritoneal metastasis in mucinous lower GI cancers

Understanding how colorectal cancers that grow from mucus-producing cells use chemicals in mucus to grow is key to developing new potential treatments.

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Targeting the mucus matrix to prevent peritoneal metastasis in mucinous lower GI cancers

Research grants

Sodium transport as a new marker of aggression in bowel cancer

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Tumour acidity and its impact on cancer treatment

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What is the role of bacteria in peritoneal metastases from colorectal cancer?

Illuminating the tissue barriers leading to treatment resistance and recurrence of bowel cancer

Investigating interactions between colorectal cancer subclones and fibroblasts

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The ‘empty pelvis syndrome’ – defining and reducing morbidity from a major cause of complications after complex pelvic cancer surgery

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Decoding extracellular matrix signatures that drive malignancy in colon cancer

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Developing NOTUM as a target for immunotherapy of bowel cancer

Identification of spatial biomarkers in colorectal cancer

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Identifying new immune therapy strategies in advanced colorectal cancer

Research grants

A clinical trial of reirradiation and chemotherapy compared to chemotherapy alone in patients with locally recurrent rectal cancer